For five seasons, Skyler endures what no partner should have to. Walt lies again and again and admits in the final episode that everything he did was out of pure enjoyment. But even with that in mind, many fans hold her marriage to Walt as sacred. Some Redditors maintain that destroying the bond between married partners is not easy to forgive.
"Skyler did cheat, and I don't think cheating is ever justified, just like Walt being a sociopathic killer is not justified," noted u/isuckatmusictheory. To the Redditor's credit, they can no more forgive Skyler for her crimes as they could Walt for his. But other fans are not so easily swayed. Many viewers conclude that it doesn't matter what the circumstances are. There is no excuse for infidelity.
"[C]heating on your spouse is the ultimate betrayal," posted u/gee_izzy. "Seriously, she cheated in her marriage," argued u/naxx78. "[T]hat's a BFD bigger than lying." Whether viewers stand with Skyler or not seems to coincide with their personal feelings about the character. It is no secret that a vocal minority enjoys insulting Skyler on the internet, and a large part of this seems to track with their feelings about Walt. In an interview with The New Yorker, Vince Gilligan concluded that fans' love for Walt negatively impacted Skyler's reception.