Mystique's familial ties were almost entirely cut from the X-Men movies. Remember that red teleporter in X-Men: First Class, Azazel? In the comics, he's the father of Mystique's son, Nightcrawler. She had another son, Graydon Creed, with longtime Wolverine antagonist Sabretooth. Creed despises his parents for abandoning him, resulting in Graydon hating everyone with an X-gene and the formation of his anti-mutant group of hatemongers, the Friends of Humanity. Mystique is also the adoptive mother of Rogue, who permanently steals Ms. Marvel's powers and psyche at Mystique's command before eventually joining the X-Men. While she does try to make amends with her children, many times it's too little too late. And if you only know Mystique from the movies, then all of this is news to you, huh?