In 2011, Mintz-Plasse landed the role of Edward "Evil Ed" Lee in the comedic remake of director Tom Holland's 1985 horror film Fright Night.

Originally, Mintz-Plasse wasn't really down with acting in a remake, but he couldn't deny the chance to act alongside the likes of Colin Farrell. "Whenever I see a trailer for a remake," Mintz-Plasse told About.com, "I'm like, 'Why can't they think of something original?' And then I read the script, and I was like, 'I love Craig Gillespie. I love Colin Farrell. I love Anton [Yelchin].'" On top of working with some big names, Mintz-Plasse is also a fan of the genre, so he caved. "It was very violent and bloody in the script," he explained, "and I'm a fan of that in a horror movie, so I said, 'Why the hell not be a part of unoriginal Hollywood?'"