After a meeting with Phil Leotardo (Frank Vincent) in New York, Christopher is driving Tony back to New Jersey when he begins veering wildly on the highway due to being high on narcotics. Unfortunately, his reckless driving causes a severe car accident and a rollover, and Christopher, who is not wearing a seatbelt, is badly injured as a result.
As Christopher fights for his breath due to internal bleeding, he tells Tony that he won't pass a drug test. Though Tony considers dialing 911, this appears to be the moment where he instead makes the choice that arguably damns his character morally for the remainder of "The Sopranos." He looks into the back seat and sees that a tree branch has impaled its way through the car seat of Christopher's daughter and kills him by holding his nose shut.
With Christopher struggling as he chokes to death on his own blood, Tony seems to show little to no remorse. In fact, he practically struggles to hold in his glee for what he has done and how easily he got away with it as the episode continues. He makes crass comments about Christopher's character to his therapist, Dr. Jennifer Melfi (Lorraine Bracco), and even talks poorly about him after his own funeral, during a wake being held at Tony's house.