The character of Joe came into the lives of "Grey's Anatomy" fans in Season 2, Episode 1, after he passes out on the floor of his bar and ends up at Seattle Grace Hospital. When he expresses fears that he can't afford the surgery needed, George O'Malley (T.R. Knight) comes up with an ingenious solution to temporarily donate Joe's body to science for the surgery so a private grant will cover the surgery. While Seasons 2 and 3 of "Grey's Anatomy" saw a lot of Joe — he appeared in 20 episodes — his character wasn't in Season 4 at all and only showed up for eight episodes between Seasons 5 and 6.

The last appearance of Joe was in Season 7, Episode 9 ("Slow Night, So Long") when Cristina Yang (Sandra Oh) is trying to learn how to be a bartender at Joe's Bar after briefly quitting the hospital. While he tries to fire her after giving away every drink for free and then drinking while she's working, she refuses to leave. In the end, her husband, Owen (Kevin McKidd), carries a drunk Cristina out of the bar, and a shared nod between him and Joe is the last time we see him.

Steven Bailey likes to think Joe moved somewhere with his husband, Walter, and their kids. "Maybe they moved to Montana or something," he joked to TV Guide. "They've got a whole bed and breakfast thing going now. Who knows? But I like to think he's still out there somewhere."